Well tolerated.2 Low side effects.2 Proven safety profile.

The most common side effect of all selective alpha-blockers
is retrograde ejaculation, or orgasm with reduced semen.17
This is an expected side effect and is not harmful to
your health. It is also reversible once you stop taking RAPAFLO®.2,16

Reduced semen does not affect the ability to orgasm, maintain
an erection, or experience pleasurable sex.1

Other possible RAPAFLO® side effects2:

  • Dizziness
  • Diarrhea
  • Lightheadedness
  • Headache
  • Throat or nasal swelling
  • Stuffy nose
  • Like all alpha-blockers, it may cause a slight drop in blood pressure, especially when you stand up quickly
You should not drive, operate machinery, or do any dangerous
activities until you know how RAPAFLO® affects you.2


In 8 out of 10 cases urinary symptoms like
frequency, urgency, and nighttime urination
are all signs of an enlarged prostate.1

*Per 30-capsule supply. Offer expires 3/31/2016. Actavis reserves the right to rescind, revoke, or amend this offer without notice at any time.
    What can I expect from RAPAFLO®?

    RAPAFLO® is a highly selective alpha-blocker that targets the prostate, so it has a low effect on other areas of the body.14,15 RAPAFLO® works quickly to relieve the symptoms of an enlarged prostate within 3 to 4 days, and then continues to improve those symptoms over time.2,3

    Why would my urologist or health care provider recommend RAPAFLO® over other medications?

    RAPAFLO® is proven to work fast and then continues to relieve and improve symptoms of an enlarged prostate over time.2,3 RAPAFLO® is safe for most men to take along with hypertension medications or with other heart medications.2,3,7

    There is no generic equivalent of RAPAFLO® Make sure you’re getting RAPAFLO® at the pharmacy.

    What are the side effects of RAPAFLO®?

    Retrograde ejaculation, reduced or no semen, is the most common side effect of RAPAFLO®. It does not affect the ability to orgasm or to have pleasurable sex and is reversible upon discontinuation.

    Other less common side effects include dizziness, diarrhea, lightheadedness upon standing or sitting up abruptly, headache, stuffy nose, and swelling of the throat and nasal passages.2

    What is retrograde ejaculation?

    The most common side effect of all selective alpha-blockers is orgasm with reduced or no semen, known as retrograde ejaculation.2 It does not affect the ability to orgasm, maintain an erection, or have pleasurable sex.1

    Reduced semen is an expected side effect, and is not harmful to your health.2,16This side effect is not permanent, and is reversible upon discontinuation.2,16

    Will RAPAFLO® affect my ability to orgasm?

    Reduced semen does NOT affect a man’s ability to achieve orgasm, or to have and maintain an erection. Although the amount of semen may be different, sex can still be pleasurable.1

    Is a generic available?

    No, there is not a generic of RAPAFLO® available. So make sure your pharmacist doesn’t try to switch you to a generic alpha-blocker that is not equivalent to RAPAFLO®. Check the label on your prescription at the pharmacy.

See More


RAPAFLO® (silodosin) capsules are indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH).

RAPAFLO® is not indicated for the treatment of hypertension.


RAPAFLO® is available only by prescription and is approved to treat male urinary symptoms due to BPH, also called an enlarged prostate. RAPAFLO® should not be used to treat high blood pressure.

Only your doctor can tell if you have BPH, not a more serious condition like prostate cancer. RAPAFLO® should not be used in patients with severe liver or kidney disease as well as those taking certain antifungal or HIV drugs. Do not take RAPAFLO® if you know you are allergic to it or any of its ingredients.

Avoid driving or hazardous tasks until you know how RAPAFLO® will affect you, as a sudden drop in blood pressure may occur, rarely resulting in fainting. If considering cataract surgery, tell your eye surgeon you're currently taking RAPAFLO® or have taken it in the past.

Side effects include a decrease or absence of semen during sex, dizziness, diarrhea, lightheadedness upon standing or sitting up abruptly, headache, swelling of the throat and nasal passages, and stuffy nose.

Please view the full Prescribing Information for RAPAFLO®.

RAPAFLO® and its design are registered trademarks of Actavis, Inc.

    1. National Institute of Diabetes and Digestive and Kidney Diseases. Prostate enlargement: benign prostatic hyperplasia.
      NIH Publication No. 07-3012. June 2006.
    2. RAPAFLO® (silodosin) Capsules full Prescribing Information, Parsippany, NJ: Watson Pharma, Inc. January 2013.
    3. Marks LS, Gittelman MC, Hill LA, Volinn W, Hoel G. Rapid efficacy of the highly selective α1A-adrenoceptor antagonist silodosin in men with signs and symptoms of benign prostatic hyperplasia: pooled results of 2 phase 3 studies. J Urol. 2009;181:2634-2640.
    4. Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol. 1984;132:474.
    5. Roehrborn CG, Kaplan SA, Lepor H, Volinn W. Symptomatic and urodynamic responses in patients with reduced or no seminal emission during silodosin treatment for LUTS and BPH. Prostate Cancer Prostatic Dis. 2011;14:143-148.
    6. Shvartzman P, Borkan JM, Stoliar L, et al. Second-hand prostatism: effects of prostatic symptoms on spouses’ quality of life, daily routines and family relationships. Family Pract. 2001;18:610-613.
    7. Data on file, Watson Laboratories, Inc.
    8. Marks LS, Gittelman MC, Hill LA, Volinn W, Hoel G. Silodosin in the treatment of the signs and symptoms of benign prostatic hyperplasia:
      a 9-month, open-label extension study. Urology. 2009;74:1318-1322.
    9. Cunha, JP. Frequent urination. eMedicine Health from WebMD. Available at: Accessed April 22, 2013.
    10. Issa MM, Regan T. Medical therapy for benign prostatic hyperplasia—present and future impact. Am J Manag Care. 2007;13:S4-S9.
    11. Fenter TC, Naslund MJ, Shah MB, Eaddy MT, Black L. The cost of treating the 10 most prevalent diseases in men 50 years of age or older.
      Am J Manag Care. 2006;12(4 suppl):S90-S98.
    12. American Urological Association. AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1: Diagnosis and treatment recommendations. J Urol. 2003;170:530-547.
    13. Medline Plus Medical Encyclopedia from NIH: Enlarged prostate. Available at: Accessed July 29, 2010.
    14. de Mey C, Michel MC, McEwen J, Moreland T. A double-blind comparison of terazosin and tamsulosin on their differential effects on ambulatory blood pressure and nocturnal orthostatic stress testing. Eur Urol. 1998;33:481-488.
    15. Milani S, Djavan B. Lower urinary tract symptoms suggestive of benign prostatic hyperplasia: latest update on α1-adrenoceptor antagonists. BJU Int. 2005;95(Suppl 4):29-36.
    16. Kobayashi K, Masumori N, Hisasue S, et al. Inhibition of seminal emission is the main cause of an ejaculation induced by a new highly selective α1A-blocker in normal volunteers. J Sex Med. 2008;5:2185-2190.
    17. Kaplan SA. Side effects of α-blocker use: retrograde ejaculation. Rev Urol. 2009;11(Suppl 1):S14-S18.
    18. JALYN (dutasteride and tamsulosin hydrochloride) Capsules full Prescribing Information, GlaxoSmithKline, October 2012.
    19. Rosen RC, Giuliano F, Cason CC. Sexual dysfunction and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Eur Urol. 2005;47:824-837.
    20. Bruskewitz RC. Quality of life and sexual function in patients with benign prostatic hyperplasia. Rev Urol. 2003;5:72-80.
    21. Kaplan S, Roehrborn CG, Hill LA, Volinn W. Effect of estimated prostate volume on silodosin-mediated improvements in the signs and symptoms of BPH: does prostate size matter? Open Access J Urol. 2011;3:89-93.
    22. American Urological Association Foundation. Prostate Health Playbook. AUA Foundation. 2011. Available at: Accessed May 17, 2013.
    23. Ponholzer A, Madersbacher S. Lower urinary tract symptoms and erectile dysfunction; links for diagnosis, management and treatment.
      Int J Impot Res. 2007;19:544-550.
    24. Kuritzky L. A primary care physician’s perspective on benign prostatic hyperplasia. Rev Urol. 2003;5(suppl 5):S42-S48.
    25. Wolters R, Wensing M, Van Weel C, Van Der Wilt GJ, Grol RPTM. Lower urinary tract symptoms: social influence is more important than symptoms in seeking medical care. BJU Int. 2002;90:655-661.